Our safety depends mainly on full awareness and common sense. I don't even think about getting on a motorcycle if I had a drink that day, even one beer. That rule prevents the slippery slope that some people might get on, i.e., well 1 drink is OK so maybe 2 is OK, etc. I don't know the stats but willing to bet a large percent get hurt and killed due to going on a spontaneous cruise after 1 too many.
Of course, good tires, and as many lights and reflectors as you can stand will improve your odds, but defensive and sober riding is all important. We do all we can, and the rest is fate.