Wow - it looks in beautiful shape, David!
I have a 78 R100/7, which is now semi-scramblerish in configuration (wide Renthal handlebars, Trawilwing D/P tires) but I've also ridden other early 80s R100 bikes and also owned an 88 R100RT monolever for a number of years.
I think that the R65 is still the more nimble bike, and when pressed harder into the corners, etc. doesn't seem to give me the eventual tendencies to "wallow" like several of the R100 bikes I've ridden, including my current one. I attribute this in part to (when properly setup) the better fork design on the 1982 R65 in terms of compliance and response to a variety of suspension inputs, and the thicker, stiffer top plate of the R65 steering head assembly compared to the stamped metal piece on the R100 bikes. On an R100 with a Toaster Tan or similar aftermarket steering head top clamp piece that is even more robust than the R65 one, I've noticed significant improvement. I may get one for my R100/7 soon anyhow as it is also to be doing duty with a sidecar.
The R100 engine is definitely slower to rev up compared to the R65, even with the lighter clutch carrier assembly from the 1981+ bikes. It definitely has a noticeable step up on the torque curve though.