I'll take the R65 to work when the weather is right. I am not set up for cold weather riding, so for much of October through March I don't take it to work.
I also try to avoid riding in the rain, mostly because of the other holes on the road. My rule of thumb is that if I can get two weather reports in the morning from separate sources that indicate it will not rain, taking the bike to work is in the cards that day. However, out-of-office meetings present a problem since I need to wear a suit and dress shoes, which are not the best of riding gear. Normally, I wear riding gear and change at the office, but that is hard to do when you have an out-of-office meeting.
I work in a large, multi-building office park. There are about four other people who commute to work on bikes on any kind of a semi-regular basis (one of whom is also in my office). The other bike-commuters I have not met.
k_enn