I recently installed a taller final drive, changing to a 32/10 ratio, and the difference across the entire range is dramatic. As mentioned earlier, the stock gearing had 4th & 5th very close together, so much so that it was often hard to tell which gear the bike was in. It also began losing steam and vibration became very unpleasant much above 60mph or so.
Now, with the taller gearing, I usually find myself running around town in 3rd, up to maybe 40-45mph, and will shift into 4th at speeds much above that. I also catch myself riding at 50+ in 4th gear without any undue strain or vibration being felt. 5th has become a "semi-overdrive", and is used basically at speeds above 55 or so. Highway speeds, while still not the R65s forte', are very smooth & vibration free up to the 75mph or so that I normally ride. I've pushed the bike up to 85+ before I start to become uncomfortable, but that might have just been me; getting too old to enjoy going that fast! And, I've noticed very little if any difficulty in starting from the line in 1st. Changing the rear end has really transformed the bike! [smiley=thumbsup.gif]