Recently I was getting bothered by a flat spot in the throttle at 60mph in top gear. I gave the 2-year-since-rebuild carbs a quick cleaning (sprayed through the bodies and jets rather than soak them) and synched them to no avail.
Rather than start messing around with the jetting, I ordered a new $6.00 snorkel for my plastic airbox top, PN: 13 72 1 337 501, which is smaller at the mouth than the two identical snorkels fitted to my stock '82. Took a couple weeks to get here from Germany...
...installed it in the dealership parking lot and rode off. The butt-dyno says that the flat spot is gone. The bike sounds much better when I give her the stick at 60mph as well.
It seems that BMW issued bulletins for fixing flat spots by first changing an intake snorkel... and eventually put the bikes out from the factory with one of the 13 72 1 337 501 snorkels installed.
If you have a mid range flat spot on an early 50 horse machine, I'd suggest trying the cheap and easy snorkel swap before messing with the jetting.