The bags themselves, should work, but the mounts for the R65/R45 are different from the R80/R100 mounts as far as the lower front "arms" that would bolt on down by the passenger/pillion footpeg area. On the R80/100, these are a bit further/longer reach and are horizontal, whereas on the R45/54 these are a bit closer in and vertical. If one was very handy with a welder & hacksaw you could probably adapt one to fit the other, though repainting would be required.
Usually easier to just wait for the proper mounts.
Also, I *think* that the Krauser bags will fit the OEM BMW mounting frames with an adapter, but am not sure.