I tried out several K100RS bikes - and agree with Mike (Phorqs) assessment. They really are solid, but also rather top heavy feeling.
The K100 bikes do have a tendency to emit a higher frequency buzz in the handlebars and somewhat through the tank/footpegs at times. Keeping the injection system properly synched helps a bit with that.
They will "cook" you if you are stuck in slow traffic on a hot day.
The K75 bikes are definitely smoother runners (no buzz) and, while they don't have the 100 HP (on this side of the pond, anyhow) that the K100 bikes do, they manage very nicely with the ~80 HP they put out. They do tend to have a high pitched "turbine/jet engine" type sound - which some people hate and some love. This sound is largely due to the counterbalancing system which keeps things so smooth. I know of several people who love their K75 bikes and rack up many miles on them. For some reason, they've all had issues at some point or another with the rear shock breaking on them (literally, breaking). My cousin owns a 1985 K100RS - has owned it since new, and has somewhere around 175K miles on it. He has had to replace the transmission and overhaul the final drive once or possible twice in that period, and he typically rides on trips that are a few thousand miles at a shot. He would never give up that bike, either.