I replaced the main jets on my '81 R65, I went from 145, to 138 .
I got a few spares when I got my '84 LS .
The US model '81 R65 was jetted the richest from what the Bing manual says .
I was experimenting to see if I would see any appreciable increase in fuel mileage, since 10% ethanol has been added to the fuel supply and I have lost 5-6 miles, 8-10 km per US gallon .
Also with the extreme heat here in the low deserts of southern Aridzona the density altitude, or the decrease of air pressure due to the less dense hot air .
Phoenix is at an altitude of 1130 feet 340 m, at an average air temp of 105-110 F, 41-43 C during our ' hot season ', it's like being at around 6,000 feet, 1800 m in elevation .
The conversion factor in the manual, would make the correct jet size a 139, so a 138 was close enough .
After I did this, I saw no change what so ever in engine operation, or any noticeable increase in fuel mileage .
So, after saying all this, I really don't think you'll see any noticeable change with your main jet size change .
With the average use of an R65, I don't think the main jet metering comes into play very much .