The R65 swingarm on the dual shock bikes is unique to the R45/R65 model line - it is shorter anyway than the R80/R100. I *think* that the pivot pins & bearings are the same as on the R80/R100 but I am not sure. The bolt patterns for attaching the final drives are compatible, so one can swap final drives etc with the larger displacement bikes, though they are generally too tall geared to work well with the R65, unless maybe you use the 3.36:1 or 3.2:1 final drives.
The spoked wheels thing is another kettle of fish. IT can be done, but the tricky spot is the front wheel - which is 18" on the R65, and 19" on the R80/R100. The usual solution is to find an R80ST front hub and use that to lace up an 18" rim. OR, you could modify a regular spoked R80 or R100 front hub and use different rotor carriers with some custom made spacers, assuming you match up the axle diameters. All it takes is money - there are some folks on the forum who are going through this process, or trying to, now.
Or, you could just put a 19" front spoked wheel on, and make some adjustments to your fender bracket, if necessary, and slide the fork tubes up in the triple tree a little bit to offset the change in rake from the larger front wheel - there are some that have done that too.
Somewhere I've got a pic of an R65LS in California painted bright yellow with wire spoke wheels - cannot find it at the moment..