You will need a R100 exhaust - which you will have to
make fit
You will will need the R100 carbs.
You would probably be recomended in getting a more approriate Final drive - i.e. that of R100.
Your R100 engine will have to be a similar age to your R65 - the old light/heavy flywheel and gearbox input shaft issue.
Some would have you believe that the 1/2 inch closer to the ground an R65 is compared to a R100, will mean that you will be scraping you R100 rockers on the deck. I would contend that this will only be an issue if:
1. You a riding on the track - i.e. racing
2. Or you are indeed a riding god and ride every at 10/10nths - in which case you will be dead by the end of the summer anyway.
3. You local roads have so much camber on them that you are already rubbing your rockers on a regular basis.
- there are plenty of ways around this issue - including ignoring it.
R65 engines can be tuned but it costs, and you still won't be able to blow a R100 away. R100 engine is the cheaper option

I have a spare R100 engine as well - but it is still in the R100......

And I am loath to break it up.
Cheers
Steve