We're fortunate that we get to adjust our idle mixture at all. I've gone over a number of carbs (some of them contemporary with our R65's) where the mixture screws are either behind a lead plug or have the little tabs on them so they interfere with the carb bracket at about a half a turn.
The VN750 I owned had the lead plugs over the screws. The factory manual called for them to be replaced after the carburetor had been reassembled.